Sepsis Induces Age- and Sex-Specific Chromatin Remodeling in Myeloid-derived Suppressor Cells
Angel M. Charles, Christine E. Rodhouse, Dijoia B. Darden, Marie‐Pierre L. Gauthier, Mingqi Zhou, Miguel Hernández-Ríos, Dayuan Wang, Gemma Casadesus, Letitia E. Bible, Alicia M. Mohr, Feifei Xiao, Guoshuai Cai, Jason Orr Brant, Shannon Margaret Wallet, Clayton E. Mathews, , Michael P. Kladde
This study maps epigenetic changes in MDSCs after sepsis, revealing age- and sex-specific chromatin remodeling linked to immune dysfunction.
bioRxiv · May 26, 2025 · PreprintImmunology