Author
University of Florida HealthORCID 0000-0003-2101-1588Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jason Orr Brant, Marie‐Pierre L. Gauthier, Christine E. Rodhouse…·Michael P. Kladde
The paper profiles chromatin accessibility in post-sepsis MDSCs, showing divergent epigenetic trajectories between rapid recovery and chronic critical illness, with MHC class II repression in CCI.
Christine Rodhouse, Evan L. Barrios, Leilani Zeumer-Spataro…·Clayton E. Mathews
This study identifies prolonged reduced oxidative metabolism and mitochondrial mass in CD66b+ leukocytes from sepsis patients, linked to adverse outcomes and gene silencing.
Christine E. Rodhouse, Dayuan Wang, Hongru Tang…·Philip Alexander Efron
This study examines age and sex effects on MDSCs in sepsis using single-cell RNA sequencing, finding differences in expansion, transcriptome, and metabolism.
Angel M. Charles, Christine E. Rodhouse, Dijoia B. Darden…·Michael P. Kladde
This study maps epigenetic changes in MDSCs after sepsis, revealing age- and sex-specific chromatin remodeling linked to immune dysfunction.