Author

Miguel Hernández-Ríos

University of Florida HealthORCID 0009-0004-2181-8773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Alicia M. MohriD· 3 shared Angel M. CharlesiD· 3 shared Christine E. RodhouseiD· 3 shared Clayton E. MathewsiD· 3 shared Feifei XiaoiD· 3 shared Guoshuai CaiiD· 3 shared Letitia E. BibleiD· 3 shared Lyle L. MoldaweriD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Alicia M. MohrORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Divergent chromatin remodeling in post-sepsis MDSCs underlies MHC class II repression in CCI

Jason Orr Brant, Marie‐Pierre L. Gauthier, Christine E. Rodhouse, Ruoxuan Wu, Miguel Hernández-Ríos, Leilani Zeumer-Spataro, Marvin L. S. Dirain, Ricardo F. Ungaro, Ivanna L. Rocha, Whittman B. Wiggins, Angel M. Charles, Feifei Xiao, Letitia E. Bible, Alicia M. Mohr, Shawn D. Larson, , Michael P. Kladde

The paper profiles chromatin accessibility in post-sepsis MDSCs, showing divergent epigenetic trajectories between rapid recovery and chronic critical illness, with MHC class II repression in CCI.

bioRxiv · Jul 2, 2026 · PreprintImmunology

Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis

Christine E. Rodhouse, Dayuan Wang, Hongru Tang, Valerie E. Polcz, Miguel Hernández-Ríos, Xuanxuan Yu, Leandro Balzano‐Nogueira, Jaimar C. Rincon, Angel M. Charles, Seiichiro Fujishima, Quan Vo, Marvin L. S. Dirain, Ricardo F. Ungaro, Dina C. Nacionales, Leilani Zeumer-Spataro, , Philip Alexander Efron

This study examines age and sex effects on MDSCs in sepsis using single-cell RNA sequencing, finding differences in expansion, transcriptome, and metabolism.

bioRxiv · Oct 6, 2025 · PreprintImmunology

Sepsis Induces Age- and Sex-Specific Chromatin Remodeling in Myeloid-derived Suppressor Cells

Angel M. Charles, Christine E. Rodhouse, Dijoia B. Darden, Marie‐Pierre L. Gauthier, Mingqi Zhou, Miguel Hernández-Ríos, Dayuan Wang, Gemma Casadesus, Letitia E. Bible, Alicia M. Mohr, Feifei Xiao, Guoshuai Cai, Jason Orr Brant, Shannon Margaret Wallet, Clayton E. Mathews, , Michael P. Kladde

This study maps epigenetic changes in MDSCs after sepsis, revealing age- and sex-specific chromatin remodeling linked to immune dysfunction.

bioRxiv · May 26, 2025 · PreprintImmunology