Author

Gemma Porter

University of Southampton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Andrés F. VallejoiD· 2 shared Ben D. MacArthuriD· 2 shared James DaviesiD· 2 shared Jonathan J. WestiD· 2 shared Kalum ClaytoniD· 2 shared Marta Ewa PolakiD· 2 shared Patrick S. StumpfiD· 2 shared Sofía SirventiD· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersSystems Biology

Andrés F. VallejoORCID

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2 papers

Recent·Most cited

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity.

James Davies, Andrés F. Vallejo, Sofía Sirvent, Gemma Porter, Kalum Clayton, Yamkela Qumbelo, Patrick S. Stumpf, Jonathan J. West, Clive M. Gray, Nyaradzo T. L. Chigorimbo‐Murefu, Ben D. MacArthur, Marta Ewa Polak

The paper identifies TNF-driven transcriptional programs in Langerhans cells that regulate immunogenic and tolerogenic responses through IRF1 and other transcription factors.

bioRxiv · Feb 7, 2021 · PreprintSystems Biology

Single cell transcriptomic analysis identifies Langerhans cells immunocompetency is critical for ability to induce tolerogenic T cells.

James Davies, Sofía Sirvent, Andrés F. Vallejo, Kalum Clayton, Gemma Porter, Patrick S. Stumpf, Jonathan J. West, Michael R. Ardern‐Jones, Harinder Singh, Ben D. MacArthur, Marta Ewa Polak

The paper identifies that Langerhans cells (LCs) upregulate a tolerogenic gene module during migration, which is critical for inducing regulatory T cells.

bioRxiv · Dec 20, 2019 · PreprintSystems Biology