Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV.
Doty B. A. Ojwach, Nicola E. Annels, Sunny Sunshine, Daniel Simpkin, Justin Duruanyanwu, Tariq Webber, Berenice Alinde, Nadia M. Ikumi, Michael Z. Zulu, Hlengiwe P. Madlala, Landon Myer, Thokozile Rosemary Malaba, Marie‐Louise Newell, Paola Campagnolo, Siamon Gordon, , Fernando O. Martínez
The paper links low placental Factor XIIIA1 expression with preterm birth in pregnant people living with HIV on long-term ART, suggesting ART may disrupt placental vascularization.
bioRxiv · Oct 30, 2024 · PreprintImmunology