Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues
Ambre Julie Sala, Rogan A. Grant, Ghania Imran, Claire M. Morton, Renée M. Brielmann, Szymon Gorgoń, Jennifer L. Watts, Laura C. Bott, Richard I. Morimoto
This study identifies NHR-49 as a regulator of stress resilience and proteostasis in C. elegans, linking lipid homeostasis to proteotoxic stress responses.
bioRxiv · Apr 25, 2023 · PreprintGenetics