Author

Laura C. Bott

Northwestern UniversityORCID 0000-0002-7032-1163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Renée M. Brielmann· 2 shared Richard I. MorimotoiD· 2 shared Ai FujimotoiD· 1 shared Akira KitamuraiD· 1 shared Ambre Julie SalaiD· 1 shared Ayumi Kurata· 1 shared Claire M. MortoniD· 1 shared Ghania Imran· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Renée M. Brielmann

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2 papers

Recent·Most cited

Molecular BiologyCommunications BiologyPeer-reviewedJun 20, 2024

Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity

Akira Kitamura, Ai Fujimoto, Rei Kawashima…·Masataka Kinjo

This study shows that truncated RRM in TDP-43 CTFs causes structural changes in IDR, leading to toxic hetero-oligomers and cell-nonautonomous toxicity in nematodes.

15 citations

𝕏 PostBluesky

GeneticsbioRxivPreprintApr 25, 2023

Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues

Ambre Julie Sala, Rogan A. Grant, Ghania Imran…·Richard I. Morimoto

This study identifies NHR-49 as a regulator of stress resilience and proteostasis in C. elegans, linking lipid homeostasis to proteotoxic stress responses.

4 citations

C. elegansproteomics

𝕏 PostBluesky