Author

Renée M. Brielmann

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Laura C. BottiD· 2 shared Richard I. MorimotoiD· 2 shared Ai FujimotoiD· 1 shared Akira KitamuraiD· 1 shared Ambre Julie SalaiD· 1 shared Ayumi Kurata· 1 shared Claire M. MortoniD· 1 shared Ghania Imran· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Laura C. BottORCID

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Author profile →

2 papers

Recent·Most cited

Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity

Akira Kitamura, Ai Fujimoto, Rei Kawashima, Yidan Lyu, Kotetsu Sasaki, Y. Hamada, Kanami Moriya, Ayumi Kurata, Kazuho Takahashi, Renée M. Brielmann, Laura C. Bott, Richard I. Morimoto, Masataka Kinjo

This study shows that truncated RRM in TDP-43 CTFs causes structural changes in IDR, leading to toxic hetero-oligomers and cell-nonautonomous toxicity in nematodes.

Communications Biology · Jun 20, 2024Peer-reviewedMolecular Biology

Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues

Ambre Julie Sala, Rogan A. Grant, Ghania Imran, Claire M. Morton, Renée M. Brielmann, Szymon Gorgoń, Jennifer L. Watts, Laura C. Bott, Richard I. Morimoto

This study identifies NHR-49 as a regulator of stress resilience and proteostasis in C. elegans, linking lipid homeostasis to proteotoxic stress responses.

bioRxiv · Apr 25, 2023 · PreprintGenetics