A Feed-forward Relay between Bicoid and Orthodenticle Regulates the Timing ofEmbryonic Patterning in Drosophila
Rhea R. Datta, Ling Jia, Jesse V. Kurland, Xiaotong Ren, Zhe Xu, Gozde Yucel, Jackie Moore, Leila Shokri, Isabel Baker, Timothy R. Bishop, Paolo Struffi, Rimma Levina, Martha L. Bulyk, Robert J. Johnston, Stephen Small
The paper identifies three classes of enhancers regulated by Bicoid and Orthodenticle in Drosophila embryos, revealing a feed-forward relay mechanism that coordinates gene expression timing.
Genes & Development · May 1, 2018Peer-reviewedMolecular Biology