Author

Zhe Xu

BGI Group (China)ORCID 0000-0002-4790-7641Unclaimed ORCID profile · follow to get notified of new preprints

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Zhe Xu1 paper · Guangzhou Laboratory

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Organism:Drosophila· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Fengping XuiD· 1 shared George McDonald ChurchiD· 1 shared Gozde Yucel· 1 shared Huajing TengiD· 1 shared Huanming YangiD· 1 shared Hui JiangiD· 1 shared Isabel BakeriD· 1 shared Jackie Moore· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Fengping XuORCID

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2 papers

Recent·Most cited

Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

Xi Xiang, Kunli Qu, Xue Liang, Xiaoguang Pan, Jun Wang, Peng Han, Zhanying Dong, Lijun Liu, Jiayan Zhong, Tao Ma, Yiqing Wang, Jiaying Yu, Xiaoying Zhao, Siyuan Li, Zhe Xu, , Yonglun Luo

The paper introduces TRAP-seq to quantify CRISPR editing efficiency and uses it to design improved gRNAs for Cas9, ABE, and CBE with high accuracy and efficiency.

bioRxiv · May 20, 2020 · PreprintSystems Biology

A Feed-forward Relay between Bicoid and Orthodenticle Regulates the Timing ofEmbryonic Patterning in Drosophila

Rhea R. Datta, Ling Jia, Jesse V. Kurland, Xiaotong Ren, Zhe Xu, Gozde Yucel, Jackie Moore, Leila Shokri, Isabel Baker, Timothy R. Bishop, Paolo Struffi, Rimma Levina, Martha L. Bulyk, Robert J. Johnston, Stephen Small

The paper identifies three classes of enhancers regulated by Bicoid and Orthodenticle in Drosophila embryos, revealing a feed-forward relay mechanism that coordinates gene expression timing.

Genes & Development · May 1, 2018Peer-reviewedMolecular Biology