Author

Grace C. Necker

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandro A. PezzuloiD· 1 shared Andrew L. ThurmaniD· 1 shared Biyun Xue· 1 shared Christine Wohlford-Lenane· 1 shared David Kyle MeyerholziD· 1 shared Huiyu GongiD· 1 shared Jian Hua ZhengiD· 1 shared Kun Li· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alejandro A. PezzuloORCID

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1 paper

Recent·Most cited

IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo

Shreya Ghimire, Biyun Xue, Kun Li, Ryan M. Gannon, Christine Wohlford-Lenane, Andrew L. Thurman, Huiyu Gong, Grace C. Necker, Jian Hua Zheng, David Kyle Meyerholz, Stanley M. Perlman, Paul B. McCray, Alejandro A. Pezzulo

This study shows IL-13 protects airway epithelial cells from SARS-CoV-2 infection in vitro but worsens disease severity in mice through eicosanoid signaling.

EBioMedicine · Sep 17, 2025Peer-reviewedCell Biology