Author
University of Exeter
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Liisi Laaniste, Joachim Luginbühl, Mi K. Trinh…·Louwai Muhammed
The paper identifies TP53 and RB1 wild-type status as predictors of cytarabine sensitivity in gliomas using CRISPRi screening and machine learning analysis.
Wenmin Zhao, Ana Solaguren-Beascoa, Grant W. A. Neilson…·Sera Aylin Cakiroglu
The paper introduces a contrastive fine-tuning method for single-cell foundation models to detect subtle transcriptomic changes in Perturb-seq data, outperforming traditional differential expression methods.
Wenmin Zhao, Ana Solaguren-Beascoa, Grant W. A. Neilson…·Sera Aylin Cakiroglu
The paper introduces dynamic token adaptation to combine single-cell foundation models with DNA-sequence embeddings to predict gene regulation in different genetic contexts.
Leonard C. Steg, Gemma L. Shireby, Jennifer L. Imm…·Eilis J. Hannon
The paper develops a novel epigenetic clock for fetal brain development to predict prenatal age in iPSCs and derived neurons, showing they remain epigenetically fetal despite differentiation.
Gemma L. Shireby, Jonathan P. Davies, Paul T. Francis…·Jonathan S. Mill
The paper develops a novel DNA methylation clock optimized for human cortex tissue, outperforming existing clocks and highlighting issues with previous associations between DNA methylation age and neurodegenerative phenotypes.