Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
Lihong Zhan, Grietje Krabbe, Fei Du, Ian Richard Jones, Meredith C. Reichert, Maria A. Telpoukhovskaia, Lay Kodama, Chao Wang, Seo-Hyun Cho, Faten A. Sayed, Yaqiao Li, David Le, Yungui Zhou, Yin Shen, Brian L. West, Li Gan
This study shows that adult microglia self-renew to restore homeostasis after ablation, with specific maturation programs and spatial organization.
PLoS Biology · Feb 8, 2019Peer-reviewedNeuroscience