Griffin S Hampton

Sulfur amino acid restriction prevents S-adenosylmethionine-driven liver steatosis, hepatocellular carcinoma, and metabolic remodeling in high-fat-fed GNMT-null mice

This study shows that sulfur amino acid restriction prevents liver steatosis and hepatocellular carcinoma in GNMT-null mice fed a high-fat diet by reducing SAM levels and metabolic dysregulation.

Hepatic ketogenesis supports liver lipid homeostasis during acute exercise but is not required for exercise training to mitigate liver steatosis in mice