Author

H. Antar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Organism:bacteria (other)· 2 Assay:DNA methylation· 2 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. Gruber· 4 shared C. Dekker· 2 shared D. Michieletto· 2 shared J. van der Torre· 2 shared M. Tisma· 2 shared R. Barth· 2 shared Y.-M. Soh· 2 shared A. Anchimiuk· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersBiophysics

S. Gruber

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dynamic ParB-DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

M. Tisma, R. Janissen, H. Antar, A. Martin Gonzalez, R. Barth, T. Beekman, J. van der Torre, D. Michieletto, S. Gruber, C. Dekker

This study investigates how ParB-DNA interactions form a dynamic partition condensate for bacterial chromosome segregation using in vitro experiments and simulations.

bioRxiv · Jun 25, 2023Biophysics

VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor

H. Antar, S. Gruber

This study identifies CTP as a cofactor for VirB, a transcriptional activator in Shigella flexneri, showing it binds CTP and promotes DNA clamp closure.

bioRxiv · May 19, 2023Microbiology

ParS-independent recruitment of the bacterial chromosome-partitioning protein ParB

M. Tisma, M. Panoukidou, H. Antar, Y.-M. Soh, R. Barth, B. Pradhan, J. van der Torre, D. Michieletto, S. Gruber, C. Dekker

This study shows ParB can recruit itself to DNA independently of parS, enabling long-distance chromosome segregation in bacteria.

bioRxiv · Nov 2, 2021Biophysics

Relief of ParB autoinhibition by parS DNA catalysis and ParB recycling by CTP hydrolysis promote bacterial centromere assembly.

H. Antar, Y.-M. Soh, S. Zamuner, F. P. Bock, A. Anchimiuk, P. De Los Rios, S. Gruber

This study investigates how CTP hydrolysis and parS DNA catalysis influence ParB clamp closure and recycling, contributing to bacterial centromere assembly.

bioRxiv · May 5, 2021Biochemistry