Author

H. B. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. P. Turnbull· 1 shared A. Pinto-Fernandez· 1 shared B. M. Kessler· 1 shared C. R. Pudney· 1 shared D. P. O'Brien· 1 shared D. Pantos· 1 shared D. Rasadean· 1 shared E. J. Murphy· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. P. Turnbull

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

D. P. O'Brien, H. B. Jones, F. Guenther, E. J. Murphy, K. S. England, M. Anderson, P. Brennan, J. B. Davis, A. Pinto-Fernandez, A. P. Turnbull, B. M. Kessler

This study investigates how a benzosulfonamide compound inhibits USP30, a mitochondrial deubiquitylating enzyme, using biochemical and structural methods to reveal its binding mechanism and selectivity.

bioRxiv · Sep 13, 2022Biochemistry

Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover

S. D. Winter, H. B. Jones, D. Rasadean, R. Crean, M. J. Danson, D. Pantos, G. Katona, E. Prentice, V. Arcus, M. van der kamp, C. R. Pudney

The paper maps how substrate interactions affect enzyme temperature dependence and global protein dynamics using a promiscuous enzyme.

bioRxiv · Jun 25, 2021Biochemistry