Author

H. B. Landsverk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. G. Syljuasen· 2 shared B. Grallert· 1 shared G. E. Rodland· 1 shared L. E. Sandquist· 1 shared L. Trinkle-Mulcahy· 1 shared L. van Bijsterveldt· 1 shared S. C. Durley· 1 shared S. Sarkar· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

R. G. Syljuasen

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2 papers

Recent·Most cited

R-loop-induced p21 expression following CDC73, CTR9, and PAF1 loss protects cancer cells against replicative catastrophe following WEE1 inhibition

L. van Bijsterveldt, H. B. Landsverk, V. Näshe, S. C. Durley, S. Sarkar, R. G. Syljuasen, T. C. Humphrey

This study identifies PAF1 complex members and p21 as key regulators of WEE1 inhibitor sensitivity, revealing their role in protecting cancer cells from replicative catastrophe through R-loop formation and DNA damage response.

bioRxiv · Jul 14, 2021 · PreprintCancer Biology

Regulation of ATR activity by the RNA polymerase II phosphatase PNUTS-PP1

H. B. Landsverk, L. E. Sandquist, G. E. Rodland, B. Grallert, L. Trinkle-Mulcahy, R. G. Syljuasen

This study shows that depletion of PNUTS-PP1 increases ATR signaling, while inhibition of CDK7 reduces it, suggesting a role for RNAPII phosphatase in regulating ATR activity.

bioRxiv · Feb 16, 2018Cancer Biology