S. T. Prigge

Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in P. falciparum persister blood stages after drug treatment

This study examines morphological changes in apicoplasts of P. falciparum persisters after drug treatment, finding that apicoplasts become enlarged and irregularly shaped during dormancy, with variations in shape and positioning over time.

Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes

This study shows that atovaquone-resistant Plasmodium falciparum mutants have severe fitness costs in mosquitoes and fail to transmit to mice, reducing the risk of drug resistance spread.

The Plasmodium falciparum apicoplast cysteine desulfurase provides sulfur for both iron sulfur cluster assembly and tRNA modification

This study identifies the dual role of Plasmodium falciparum SufS in providing sulfur for both FeS cluster assembly and tRNA modification in the apicoplast.

The mitochondrion of Plasmodium falciparum generates essential acetyl-CoA for protein acetylation

This study shows that mitochondria in Plasmodium falciparum produce essential acetyl-CoA for protein acetylation, highlighting their role in parasite survival.

Critical Role for Isoprenoids in Apicoplast Biogenesis by Malaria Parasites

This study identifies a critical role for isoprenoids in apicoplast biogenesis in malaria parasites, showing that IPP and polyprenols are essential for apicoplast membrane fluidity and inheritance.