Author

H. C. Bwanika

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Y.- L. Tsai· 1 shared A.-S. Jemth· 1 shared C. B. Paulin· 1 shared C. Dirks· 1 shared D. Boström· 1 shared E. J. Homan· 1 shared E. J. Mellerowicz· 1 shared E. Linde· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

A. Y.- L. Tsai

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Author profile →

2 papers

Recent·Most cited

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

S. M. Zhang, C. B. Paulin, M. Michel, P. Marttila, M. Yagüe-Capilla, H. C. Bwanika, H. Shu, R. Papagudi Vekatram, E. Wiita, A.-S. Jemth, I. Almlöf, O. Loseva, F. Ortis, C. Dirks, T. Koolmeister, , S. G. Rudd

This paper identifies and evaluates small-molecule inhibitors of SAMHD1 through a comprehensive screening pipeline, revealing a novel mode of inhibition and potential therapeutic applications.

bioRxiv · Jan 17, 2023 · PreprintBiochemistry

PcGCE is a potent elicitor of defense responses in aspen

E. N. Donev, M. Derba-Maceluch, X. Liu, H. C. Bwanika, I. Dobrowolska, M. Thapa, J. Lesniewska, J. Simura, A. Y.- L. Tsai, D. Boström, L. A. Kleczkowski, M. E. Eriksson, K. Ljung, E. R. Master, E. J. Mellerowicz

This paper shows that PcGCE, a microbial enzyme, acts as a pathogen-associated molecular pattern in aspen, triggering immune responses and growth retardation when expressed in transgenic plants.

bioRxiv · Sep 23, 2021 · PreprintBioengineering