Author

H. E. Gendelman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. M. DeLeo· 1 shared A. N. Bade· 1 shared A. Szlachetka· 1 shared B. D. Kevadiya· 1 shared B. J. Edagwa· 1 shared B. L. Dyavar Shetty· 1 shared B. Sillman· 1 shared C. Gurumurthy· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiochemistry

A. M. DeLeo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lipophilic Nanocrystal Prodrug-Release Defines the Extended Pharmacokinetic Profiles of a Year-Long Cabotegravir

N. Gauram, J. M. McMillan, D. Kumar, A. N. Bade, Q. Pan, T. A. Kulkarni, W. Li, N. A. Smith, B. L. Dyavar Shetty, B. Sillman, A. Szlachetka, B. J. Edagwa, H. E. Gendelman, Y. Alnouti

This study demonstrates that a nanoformulated CAB prodrug (NM2CAB) maintains plasma levels above the inhibitory concentration for up to one year, with sustained drug retention in tissues and macrophages.

Nature Communications · Jun 8, 2021Peer-reviewedPharmacology & Toxicology

Exonic Disruption Facilitates Antiviral CRISPR-Cas9 Activity for Multistrain HIV-1 Elimination

J. Herskovitz, M. Hasan, M. Patel, W. R. Blomberg, J. D. Cohen, J. Machhi, D. Stein, E. A. Schroder, J. McMillan, C. Gurumurthy, B. D. Kevadiya, H. E. Gendelman

This paper designs CRISPR-Cas9 guide RNAs targeting HIV-1 exons to reduce viral load in infected cells without off-target effects.

bioRxiv · Jan 14, 2021Microbiology

Proteomic and Biological Profiling of Extracellular Vesicles from Alzheimer’s Disease Human Brain Tissues

S. Muraoka, A. M. DeLeo, M. K. Sethi, K. Yukawa-Takamatsu, Z. Yang, J. Ko, J. D. Hogan, Z. Ruan, Y. You, Y. K. Wang, M. Medalla, S. Ikezu, W. Xia, S. Gorantla, H. E. Gendelman, , T. Ikezu

The paper profiles proteomic and biological features of extracellular vesicles from Alzheimer’s disease and control brain tissues, identifying new signature proteins associated with AD.

bioRxiv · Aug 15, 2019Biochemistry