Author

Y. Alnouti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

A. E. Dean· 1 shared A. N. Bade· 1 shared A. Szlachetka· 1 shared B. J. Edagwa· 1 shared B. L. Dyavar Shetty· 1 shared B. Sillman· 1 shared D. Kumar· 1 shared E. Gentry· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. E. Dean

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Author profile →

2 papers

Recent·Most cited

Lipophilic Nanocrystal Prodrug-Release Defines the Extended Pharmacokinetic Profiles of a Year-Long Cabotegravir

N. Gauram, J. M. McMillan, D. Kumar, A. N. Bade, Q. Pan, T. A. Kulkarni, W. Li, N. A. Smith, B. L. Dyavar Shetty, B. Sillman, A. Szlachetka, B. J. Edagwa, H. E. Gendelman, Y. Alnouti

This study demonstrates that a nanoformulated CAB prodrug (NM2CAB) maintains plasma levels above the inhibitory concentration for up to one year, with sustained drug retention in tissues and macrophages.

Nature Communications · Jun 8, 2021Peer-reviewedPharmacology & Toxicology

Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and females.

M. E. Patton, S. Kelekar, L. J. Taylor, A. E. Dean, Q. Zuo, R. N. Thakare, S. H. Lee, E. Gentry, M. Panitchpakdi, P. Dorrestein, Y. Alnouti, Z. Madak-Erdogan, J.-S. Lee, M. J. Finegold, S. Anakk

This study identifies sex-specific bile acid metabolism differences that protect female livers from liver cancer and suggests targeting bile acid excretion as a therapeutic strategy.

bioRxiv · Jun 25, 2020Cancer Biology