A novel PD-L1-targeted shark VNAR single domain-based CAR-T strategy for treating breast cancer and liver cancer
D. Li, H. English, J. Hong, T. Liang, G. Merlino, C.-P. Day, M. Ho
This paper develops a PD-L1-targeted shark VNAR-based CAR-T strategy that effectively targets breast and liver cancer cells and reduces tumor metastasis in mice.
bioRxiv · Jul 20, 2021Cancer Biology