Host-dependent induction of disease tolerance to infection by tetracycline antibiotics
H. G. Colaco, A. Barros, A. Neves-Costa, E. Seixas, D. Pedroso, T. R. Velho, K. Willmann, H.-S. Yi, M. Shong, V. Benes, S. Weis, T. Köcher, L. F. Moita
This study shows tetracycline antibiotics protect against sepsis by inducing disease tolerance through mitochondrial protein synthesis inhibition, independent of their direct antibiotic effects.
bioRxiv · Nov 7, 2019Immunology