Author

E. Seixas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Barros· 2 shared A. Neves-Costa· 2 shared D. Pedroso· 2 shared H. G. Colaco· 2 shared H.-S. Yi· 2 shared L. F. Moita· 2 shared M. Shong· 2 shared R. Martins· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Barros

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Massive lateral gene transfer under strain coexistence in the gut

N. Frazao, E. Seixas, H. Barreto, M. Mischler, D. Guleresi, I. Gordo

The paper studies how two distinct E. coli strains coexist in the mouse gut and finds strain-specific evolutionary modes and significant lateral gene transfer.

bioRxiv · Sep 25, 2023 · PreprintEvolutionary Biology

A HYPOMETABOLIC DEFENSE STRATEGY AGAINST PLASMODIUM INFECTION

S. Ramos, T. W. Ademolue, E. Jentho, Q. Wu, J. Guerra, R. Martins, G. Pires, S. Weis, A. R. Carlos, I. Mahu, E. Seixas, D. Duarte, F. Rajas, S. Cardoso, A. G. Sousa, , M. P. Soares

The paper shows that Plasmodium infection induces hypoglycemia in mice through heme-driven suppression of hepatic glucose production, which limits parasite growth but promotes gametocyte production.

bioRxiv · Sep 8, 2021Immunology

Host-dependent induction of disease tolerance to infection by tetracycline antibiotics

H. G. Colaco, A. Barros, A. Neves-Costa, E. Seixas, D. Pedroso, T. R. Velho, K. Willmann, H.-S. Yi, M. Shong, V. Benes, S. Weis, T. Köcher, L. F. Moita

This study shows tetracycline antibiotics protect against sepsis by inducing disease tolerance through mitochondrial protein synthesis inhibition, independent of their direct antibiotic effects.

bioRxiv · Nov 7, 2019Immunology

CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

I. Santos, H. G. Colaco, A. Neves-Costa, E. Seixas, T. R. Velho, D. Pedroso, A. Barros, R. Martins, S. Weiss, D. Payen, S. Weiss, H.-S. Yi, M. Shong, L. F. Moita

This study shows that GDF15 deficiency in mice protects against abdominal sepsis by enhancing CXCL5-mediated neutrophil recruitment to the peritoneum, improving bacterial control.

bioRxiv · Aug 12, 2019Immunology