Author

H. H. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Basle· 1 shared A. Yildirim· 1 shared B. J. Curtis· 1 shared C. J. Wrobel· 1 shared D. J. Campopiano· 1 shared E. Johnson· 1 shared E. L. Johnson· 1 shared E. S. Ozdemir· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. Basle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In silico screening and testing of FDA approved small molecules to block SARS-CoV-2 entry to the host cell by inhibiting Spike protein cleavage

E. S. Ozdemir, H. H. Le, A. Yildirim, S. V. Ranganathan

This study uses a computational pipeline to identify FDA-approved drugs that inhibit SARS-CoV-2 Spike protein cleavage, reducing protease activity and potentially preventing viral entry.

bioRxiv · Mar 7, 2022Biophysics

Inositol lipid synthesis is widespread in host-associated Bacteroidetes

S. L. Heaver, H. H. Le, P. Tang, A. Basle, J. Marles-Wright, E. Johnson, D. J. Campopiano, R. E. Ley

This study identifies two pathways for inositol lipid synthesis in host-associated Bacteroidetes, showing their prevalence and potential role in host interactions.

bioRxiv · Apr 26, 2021 · PreprintMicrobiology

Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles

H. H. Le, C. J. Wrobel, S. M. Cohen, J. Yu, H. Park, M. J. Helf, B. J. Curtis, J. Kruempel, P. R. Rodrigues, P. J. Hu, P. W. Sternberg, F. C. Schroeder

The paper identifies carboxylesterases and lysosome-related organelles as essential for modular metabolite assembly in C. elegans, including ascarosides and glucosides.

bioRxiv · Aug 22, 2020 · PreprintBiochemistry

Dietary sphinganine is selectively assimilated by members of the gut microbiome

M.-T. Lee, H. H. Le, E. L. Johnson

The paper tracks dietary sphinganine assimilation by gut microbes using ClickSSS, revealing Bacteroides as the primary assimilators.

bioRxiv · Jun 8, 2020Microbiology