In silico screening and testing of FDA approved small molecules to block SARS-CoV-2 entry to the host cell by inhibiting Spike protein cleavage
E. S. Ozdemir, H. H. Le, A. Yildirim, S. V. Ranganathan
This study uses a computational pipeline to identify FDA-approved drugs that inhibit SARS-CoV-2 Spike protein cleavage, reducing protease activity and potentially preventing viral entry.
bioRxiv · Mar 7, 2022Biophysics