Author

A. Yildirim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Quentel· 1 shared A.-K. Wallisch· 1 shared B. P. Branchaud· 1 shared B. R. Kingston· 1 shared C. Mavili· 1 shared E. H. Finn· 1 shared E. S. Ozdemir· 1 shared E. Unver· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Quentel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

L. Xiang, M. Stewart, K. Mooney, M. Dai, S. Drennan, S. Holland, A. Quentel, S. Sabuncu, B. R. Kingston, I. Dengos, K. Bonic, F. Goncalves, X. Yi, S. Ranganathan, B. P. Branchaud, , A. Yildirim

This study demonstrates that peptide amphiphile nanostructures enhance cancer imaging and therapy by hitchhiking on endogenous biomolecules to target tumors effectively.

bioRxiv · Feb 21, 2024 · PreprintBioengineering

Reliability metrics of outcome measures during the single and double leg drop jump tests

H. Celik, A. Yildirim, E. Unver, C. Mavili, E. Yilmaz, F. Ozturk, P. Arpinar-Avsar, S. A. Cinemre

This study assesses the reliability of outcome measures in single and double leg drop jump tests for collegiate athletes, finding high reliability for key metrics in both tests.

bioRxiv · Jul 10, 2022 · PreprintPhysiology

In silico screening and testing of FDA approved small molecules to block SARS-CoV-2 entry to the host cell by inhibiting Spike protein cleavage

E. S. Ozdemir, H. H. Le, A. Yildirim, S. V. Ranganathan

This study uses a computational pipeline to identify FDA-approved drugs that inhibit SARS-CoV-2 Spike protein cleavage, reducing protease activity and potentially preventing viral entry.

bioRxiv · Mar 7, 2022Biophysics

Integrative Genome Modeling Platform reveals essentialityof rare contact events in 3D genome organizations

L. Boninsegna, A. Yildirim, G. Polles, S. A. Quinodoz, E. H. Finn, M. Guttman, X. J. Zhou, F. Alber

The paper develops a multi-modal data integration approach to improve genome structure modeling and shows that rare contact events are essential for predicting nuclear architecture.

bioRxiv · Aug 22, 2021Biophysics

SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes

A. Yildirim, S. Mozaffari-Jovin, A.-K. Wallisch, J. Ries, S. Ludwig, H. Urlaub, R. Luehrmann, U. Wolfrum

This study identifies SANS as a regulator of pre-mRNA splicing by facilitating the transfer of tri-snRNP complexes between Cajal bodies and nuclear speckles, linking it to Usher syndrome pathophysiology.

bioRxiv · Nov 11, 2020Cell Biology