Author

L. Olsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

N. Rohner· 5 shared H. Hassan· 4 shared J. Krishnan· 3 shared A. Kenzior· 2 shared J. Persons· 2 shared R. Peuss· 2 shared Y. Wang· 2 shared A. Gluesenkamp· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersEvolutionary Biology

N. Rohner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cross-species comparison of pregnancy-induced GDF15

A. Klein, P. Ranea-Robles, T. Nicolaisen, C. Gil, K. Johann, J. Quesada, N. Pistolevij, K. Hviid, L. Olsen, S. Offersen, J. Helge, H. Svarre-Nielsen, J. Bakker, M. Kleinert, C. Clemmensen

This study compares GDF15 expression during pregnancy across species, finding significant differences in plasma levels and expression between humans/macacaques and rodents.

bioRxiv · Jun 19, 2023Physiology

The Mexican Cavefish Mount a Rapid and Sustained Regenerative Response Following Skeletal Muscle Injury

L. Olsen, H. Hassan, S. Keaton, N. Rohner

The paper investigates the regenerative response of skeletal muscle in Mexican cavefish following injury, focusing on satellite cell behavior and regeneration mechanisms.

bioRxiv · Feb 5, 2023Evolutionary Biology

Circadian rhythm disruption is associated with skeletal muscle dysfunction within the blind Mexican Cavefish

L. Olsen, J. Krishnan, H. Hassan, C. Banks, N. Rohner

This study investigates circadian-regulated gene expression in skeletal muscle of cavefish and surface fish to determine if muscle dysfunction is due to circadian disruption.

bioRxiv · Jan 25, 2023 · PreprintEvolutionary Biology

Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation

J. Krishnan, Y. Wang, O. Kenzior, H. Hassan, L. Olsen, D. Tsuchiya, Y. Wang, C. Zhao, N. Rohner

The paper develops liver-derived cell lines from cavefish Astyanax mexicanus to study metabolic adaptation and provides their characterization.

Scientific Reports · Jun 16, 2022Peer-reviewedEvolutionary Biology

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

L. Olsen, M. Levy, J. K. Medley, H. Hassan, R. Alexander, E. Wilcock, K. Yi, L. Florens, S. McKinney, R. Peuss, J. Persons, A. Kenzior, E. Maldonado, A. Gluesenkamp, E. Mager, , N. Rohner

This paper shows cavefish have reduced muscle mass and contractility but increased muscular endurance due to metabolic reprogramming involving glycogen utilization.

bioRxiv · Mar 12, 2022Evolutionary Biology

Enhanced lipogenesis through Pparγ helps cavefish adapt to food scarcity.

S. Xiong, W. Wang, A. Kenzior, L. Olsen, J. Krishnan, J. Persons, K. Medley, R. Peuss, Y. Wang, S. Chen, N. Zhang, N. Thomas, J. Miles, A. Sanchez Alvarado, N. Rohner

This study shows that cavefish enhance lipogenesis via upregulated Pparγ to store more fat, aiding adaptation to nutrient scarcity.

bioRxiv · Apr 27, 2021Evolutionary Biology