Author

H. Hengel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:proteomics· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

P. Kolb· 4 shared A. Maul-Pavicic· 2 shared K. Hoffmann· 2 shared R. E. Voll· 2 shared U. Salzer· 2 shared V. T. K. Le-Trilling· 2 shared A. Barber-Axthelm· 1 shared A. Busse Grawitz· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

P. Kolb

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity

C. E. Otero, S. Petkova, M. Ebermann, H. Taher, N. John, K. Hoffmann, A. Davalos, M. J. Mostrom, R. M. Gilbride, C. Papen, A. Barber-Axthelm, E. A. Scheef, R. Barfield, L. M. Sprehe, S. Kendall, , P. Kolb

This study identifies and characterizes Rhesus CMV-encoded Fcγ-binding glycoproteins, showing they delay antibody-mediated immune control during primary infection.

Nature Communications · Jan 31, 2025Peer-reviewedMicrobiology

Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning

C. Gerke, L. Bauersfeld, V. Oberhardt, C. Jürges, R. Spaapen, C. Mussolino, V. T. K. Le-Trilling, M. Trilling, L. Dölken, F. Erhard, M. Hofmann, H. Hengel, F. Momburg, A. Halenius

This study investigates how HCMV US10 protein regulates HLA-I genotype and surface expression, revealing its multimodal effects on different HLA-I allotypes.

bioRxiv · Jan 10, 2023Microbiology

Circulating multimeric immune complexes drive immunopathology in COVID-19

J. Ankerhold, S. Giese, P. Kolb, A. Maul-Pavicic, R. E. Voll, N. Goeppert, K. Ciminski, C. Kreutz, A. Lother, U. Salzer, W. Bildl, T. Welsink, N. Morgenthaler, A. Busse Grawitz, D. Huzly, , V. Falcone

This paper identifies soluble immune complexes as drivers of immunopathology in severe COVID-19 by enhancing FcγRIII activation and forming a vicious cycle of inflammation.

bioRxiv · Jun 25, 2021 · PreprintImmunology

Detection and functional resolution of soluble multimeric immune complexes by a comprehensive FcγR reporter cell panel

H. Chen, A. Maul-Pavicic, M. Holzer, M. Huber, U. Salzer, N. Chevalier, R. E. Voll, H. Hengel, P. Kolb

This study establishes a comprehensive FcγR reporter cell assay to detect and quantify soluble immune complexes in experimental and clinical settings.

bioRxiv · Nov 11, 2020 · PreprintImmunology

Human Cytomegalovirus antagonizes activation of Fcγ receptors II and III by distinct and synergizing modes of IgG manipulation

P. Kolb, K. Hoffmann, A. Sievert, H. Reinhard, E. Merce-Maldonado, V. T. K. Le-Trilling, D. Guetle, H. Hengel

This paper shows HCMV uses gp34 and gp68 to block FcγR activation by different mechanisms that work together to evade antibody-mediated immunity.

bioRxiv · Oct 12, 2020Microbiology