Author

E. Maniati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Lockley· 2 shared A. White· 1 shared B. Malacrida· 1 shared C. Butterworth· 1 shared C. Trevisan· 1 shared E. H. Puttock· 1 shared E. J. Tyler· 1 shared E. Peerani· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

M. Lockley

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Author profile →

3 papers

Recent·Most cited

Extracellular matrix educates a tumor macrophage phenotype found in ovarian cancer metastasis

E. H. Puttock, E. J. Tyler, M. Manni, E. Maniati, C. Butterworth, E. Peerani, P. Hirani, V. Gauthier, Y. Liu, G. Maniscalco, V. Rajeeve, P. Cutillas, C. Trevisan, M. Pozzobon, M. Lockley, , O. M. T. Pearce

The paper shows that the tumor extracellular matrix educates macrophages to adopt a phenotype seen in ovarian cancer metastasis, affecting T cell function and immune regulation.

bioRxiv · Aug 11, 2022 · PreprintCancer Biology

Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

R. Delaine-Smith, E. Maniati, B. Malacrida, S. Nichols, R. Roozitalab, R. R. Jones, L. Lecker, O. M. Pearce, M. M. Knight, F. R. Balkwill

The paper models how TGFβR and Hh pathways regulate ECM molecules in ovarian cancer using tri-culture models and identifies inhibitor combinations that reduce fibroblast activation and ECM remodeling.

bioRxiv · Feb 1, 2021Cancer Biology

Platinum resistance induces diverse evolutionary trajectories in high grade serous ovarian cancer

J. I. Hoare, H. Hockings, J. Saxena, V. L. Silva, E. Maniati, H. B. Mirza, W. Huang, G. E. Wood, F. Nicolini, T. A. Graham, I. A. McNeish, M. Lockley

This study investigates platinum resistance in high grade serous ovarian cancer by analyzing transcriptomic features and evolutionary trajectories in resistant models.

bioRxiv · Jul 23, 2020 · PreprintCancer Biology