Author

H. Hongo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Gojobori· 2 shared N. Arakawa· 2 shared Y. Terai· 2 shared B. J. Lee· 1 shared B. Popescu· 1 shared C. A. C. Peretz· 1 shared C. C. Smith· 1 shared C. Luck· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersEvolutionary Biology

J. Gojobori

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genome analysis of the Jomon dogs reveals the oldest domestic dog lineage in Eastern Eurasia

Y. Terai, X. Xiaokaiti, J. Gojobori, N. Arakawa, T. Sato, K. Kasai, K. Machida, K. Yamazaki, N. Yamaji, H. Hongo, T. Gakuhari

This study analyzes ancient Jomon dog genomes to reveal their lineage and contribution to modern dog genomes, finding they are one of the oldest East Eurasian lineages with significant genetic influence.

bioRxiv · Sep 29, 2023 · PreprintEvolutionary Biology

Allosteric SHP2 Inhibition Increases Apoptotic Dependency on BCL2 and Synergizes with Venetoclax in FLT3- and KIT- Mutant AML

B. Popescu, C. Stahlhut, T. C. Tarver, S. Wishner, B. J. Lee, C. A. C. Peretz, C. Luck, P. Phojanakong, J. A. Camara Serrano, H. Hongo, J. M. Rivera, S. Xirenayi, J. A. Chukinas, V. Steri, S. K. Tasian, , C. C. Smith

This study shows that combining SHP2 and BCL2 inhibition synergistically kills FLT3- and KIT-mutant AML cells and xenografts.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology

The Japanese wolf is most closely related to modern dogs and its ancestral genome has been widely inherited by dogs throughout East Eurasia

J. Gojobori, N. Arakawa, X. Xiayire, Y. Matsumoto, S. Matsumura, H. Hongo, N. Ishiguro, Y. Terai

This study analyzes the genomes of Japanese wolves and dogs to show that Japanese wolves are closely related to modern dogs and contributed ancestry to East Eurasian dogs.

bioRxiv · Oct 10, 2021Evolutionary Biology