Author

K. Machida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

H. Imataka· 3 shared H. Taguchi· 2 shared A. J. Carlos· 1 shared A. Lee· 1 shared A. Ohashi· 1 shared A. Yamakawa· 1 shared C. Hirayama· 1 shared D. Jung· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiochemistry

H. Imataka

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Genome analysis of the Jomon dogs reveals the oldest domestic dog lineage in Eastern Eurasia

Y. Terai, X. Xiaokaiti, J. Gojobori, N. Arakawa, T. Sato, K. Kasai, K. Machida, K. Yamazaki, N. Yamaji, H. Hongo, T. Gakuhari

This study analyzes ancient Jomon dog genomes to reveal their lineage and contribution to modern dog genomes, finding they are one of the oldest East Eurasian lineages with significant genetic influence.

bioRxiv · Sep 29, 2023 · PreprintEvolutionary Biology

Reconstitution of C9orf72 (GGGGCC) repeat-associated non-AUG translation with purified components.

H. Ito, K. Machida, M. Ueyama, Y. Nagai, H. Imataka, H. Taguchi

This study reconstitutes G4C2 repeat-associated non-AUG translation using purified human factors and identifies key features of the process.

bioRxiv · May 29, 2023 · PreprintBiochemistry

Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes

Y. Ito, Y. Chadani, T. Niwa, A. Yamakawa, K. Machida, H. Imataka, H. Taguchi

The paper shows that nascent peptides with consecutive D/E residues can cause translation discontinuation in eukaryotes, leading to biased amino acid usage in proteomes.

bioRxiv · Jan 27, 2022Biochemistry

GRP78 binds SARS-CoV-2 Spike protein and ACE2 and GRP78 depleting antibody blocks viral entry and infection in vitro

A. J. Carlos, D. P. Ha, D.-W. Yeh, R. Van Krieken, P. Gill, K. Machida, A. Lee

bioRxiv · Jan 20, 2021Microbiology

Distinct roles and actions of PDI family enzymes in catalysis of nascent-chain disulfide formation

C. Hirayama, K. Machida, K. Noi, T. Murakawa, M. Okumura, T. Ogura, H. Imataka, K. Inaba

This study compares the efficiency of PDI and ERp46 in catalyzing disulfide bond formation in nascent chains during translation, showing ERp46 is more effective early on.

bioRxiv · Jan 4, 2021Biochemistry

Cultivating in situ triggers growth of previously uncultivated microorganisms via a growth initiation factor in nature

D. Jung, K. Machida, Y. Nakao, T. Kindaichi, A. Ohashi, Y. Aoi

This study isolates previously uncultivated marine microbes using in situ cultivation and identifies growth initiation factors in sponge extracts that trigger resuscitation from dormancy.

bioRxiv · Mar 28, 2019 · PreprintMicrobiology