Author

J. A. Camara Serrano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. Stieglitz· 2 shared P. Phojanakong· 2 shared V. Steri· 2 shared A. Barpanda· 1 shared A. Izgutdina· 1 shared A. Kang· 1 shared A. Sobh· 1 shared A. Vijayanarayanan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

E. Stieglitz

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2 papers

Recent·Most cited

Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells

C. Kasap, A. Izgutdina, B. Patino-Escobar, A. Kang, N. Chilakapati, N. Akagi, H. Johnson, T. Rashid, J. Werner, A. Barpanda, H. Geng, Y.-H. T. Lin, S. Rampersaud, D. Gil-Alos, A. Sobh, , A. Wiita

Structure-optimized CD27-based CAR-T cells targeting CD70 show >80-fold improved expansion in vivo and offer a potential therapy for high-risk multiple myeloma patients.

bioRxiv · Feb 24, 2024Cancer Biology

Allosteric SHP2 Inhibition Increases Apoptotic Dependency on BCL2 and Synergizes with Venetoclax in FLT3- and KIT- Mutant AML

B. Popescu, C. Stahlhut, T. C. Tarver, S. Wishner, B. J. Lee, C. A. C. Peretz, C. Luck, P. Phojanakong, J. A. Camara Serrano, H. Hongo, J. M. Rivera, S. Xirenayi, J. A. Chukinas, V. Steri, S. K. Tasian, , C. C. Smith

This study shows that combining SHP2 and BCL2 inhibition synergistically kills FLT3- and KIT-mutant AML cells and xenografts.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology