Author

N. Raju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 7

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 6 Approach:experimental assay· 5 Assay:proteomics· 5 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

I. S. Georgiev· 6 shared J. E. Crowe· 5 shared R. H. Carnahan· 5 shared A. R. Shiakolas· 4 shared K. J. Kramer· 4 shared N. Suryadevara· 4 shared D. Wrapp· 3 shared J. S. McLellan· 3 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersImmunology

I. S. Georgiev

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Development of LIBRA-seq for the Guinea Pig Model System as a Tool for the Evaluation of Antibody Responses to Multivalent HIV-1 Vaccines

M. J. Vukovich, N. Raju, P. Kgagudi, N. P. Manamela, A. A. Abu-Shmais, K. R. Gripenstraw, P. T. Wasdin, S. Shen, B. Dwyer, J. Akoad, R. M. Lynch, D. C. Montefiori, S. I. Richardson, P. L. Moore, I. S. Georgiev

This paper evaluates multivalent HIV-1 Env immunization strategies in guinea pigs and adapts LIBRA-seq for antibody discovery, finding optimal cocktail sizes and identifying public clonotypes.

bioRxiv · Sep 25, 2023Immunology

Neutralization Fingerprinting Technology for Characterizing Polyclonal Antibody Responses to Dengue Vaccines

N. Raju, X. Zhan, S. Das, L. Karwal, H. Dean, J. E. Crowe, R. H. Carnahan, I. Georgiev

This study presents a computational framework to analyze neutralizing antibody specificities in response to dengue vaccines, revealing differences in immune responses based on prior infection status.

bioRxiv · Dec 2, 2021Immunology

Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine

K. J. Kramer, E. M. Wilfong, K. Voss, S. Barone, A. R. Shiakolas, N. Raju, C. E. Roe, N. Suryadevara, L. M. Walker, S. C. Wall, A. Paulo, S. Schaefer, D. Dahunsi, C. S. Westlake, J. E. Crowe, , J. M. Irish

bioRxiv · Jul 28, 2021Immunology

Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking

A. R. Shiakolas, N. Johnson, K. J. Kramer, N. Suryadevara, D. Wrapp, S. Periasamy, K. A. Pilewski, N. Raju, R. Nargi, R. E. Sutton, L. Walker, I. Setliff, J. E. Crowe, A. Bukreyev, R. H. Carnahan, , I. S. Georgiev

This study demonstrates that integrating ligand blocking into LIBRA-seq improves the efficiency of identifying potent SARS-CoV-2 neutralizing antibodies.

bioRxiv · Jun 2, 2021 · PreprintImmunology

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with a unique genetic signature and structural mode of spike recognition

K. J. Kramer, N. V. Johnson, A. R. Shiakolas, N. Suryadevara, S. Periasamy, N. Raju, J. K. Williams, D. Wrapp, S. J. Zost, C. M. Holt, C.-L. Hsieh, R. E. Sutton, A. Paulo, E. Davidson, B. J. Doranz, , I. S. Georgiev

This study identifies a potent SARS-CoV-2 antibody, 54042-4, that neutralizes variants of concern and has a unique epitope and genetic structure.

bioRxiv · May 16, 2021Immunology

Sequence and functional characterization of a public HIV-specific antibody clonotype

A. A. Murji, N. Raju, J. S. Qin, H. Kaldine, K. Janowska, E. F. Fechter, R. Mapengo, C. Scheepers, I. Setliff, P. Acharya, L. Morris, I. S. Georgiev

The paper characterizes a public HIV-specific antibody clonotype from three individuals, showing that antigen specificity is modulated by VH germline genes and that non-native heavy-light chain pairings maintain consistent antigen recognition.

bioRxiv · May 14, 2021Immunology

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

A. R. Shiakolas, K. J. Kramer, D. Wrapp, S. I. Richardson, A. Schäfer, S. Wall, N. Wang, K. Janowska, K. A. Pilewski, R. Venkat, R. Parks, N. P. Manamela, N. Raju, E. Friedman Fechter, C. M. Holt, , I. S. Georgiev

The paper identifies cross-reactive antibodies against multiple coronaviruses, showing they target diverse epitopes and mediate effector functions.

bioRxiv · Dec 20, 2020 · PreprintImmunology