Author

H. Kawakami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. Xu· 1 shared D. Corcoran· 1 shared D. Oikawa· 1 shared F. Tokunaga· 1 shared H. Maruyama· 1 shared J. Zhang· 1 shared K. Oda· 1 shared M. Fukushi· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

C. Xu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection

M. Fukushi, R. Ohsawa, Y. Okinaka, D. Oikawa, T. Kiyono, M. Moriwaki, T. Irie, K. Oda, Y. Kamei, F. Tokunaga, Y. Sotomaru, H. Maruyama, H. Kawakami, T. Sakaguchi

This study shows that optineurin deficiency leads to IFNβ overproduction and increased survival in mice during viral infection due to impaired autophagy.

bioRxiv · Mar 13, 2023 · PreprintImmunology

Structural insights into AT-rich DNA recognition by SALL family proteins

W. Ru, T. Koga, X. Wang, Q. Guo, M. Gearhart, S. Zhao, M. Murphy, H. Kawakami, D. Corcoran, J. Zhang, Z. Zhu, X. Yao, Y. Kawakami, C. Xu

The paper presents crystal structures of SALL family proteins bound to AT-rich DNA, revealing their recognition mechanism and functional importance in cell fate control.

bioRxiv · Jun 13, 2022 · PreprintBiochemistry