Author

H. Mostafa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:genome assembly· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Pekosz· 2 shared A. L. Tchir· 1 shared B. Sie· 1 shared C. Han· 1 shared D. Monaco· 1 shared H. B. Larman· 1 shared H. Liu· 1 shared J. Girish· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Pekosz

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2 papers

Recent·Most cited

Clade-defining mutations in human H1N1 hemagglutinin protein from 2021-2023 have opposing effects on in vitro fitness and antigenic drift

N. J. Swanson, J. Girish, M. Yunker, H. Liu, J. Norton, C. Han, H. Mostafa, K. Fenstermacher, R. E. Rothman, A. Pekosz

This study identifies clade-defining mutations in H1N1 hemagglutinin that improve viral fitness but reduce neutralization by vaccine-induced antibodies, revealing an evolutionary trade-off between replication and immune evasion.

bioRxiv · May 18, 2024 · PreprintMicrobiology

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping

J. J. Credle, M. Robinson, J. Gunn, D. Monaco, B. Sie, A. L. Tchir, J. Hardick, X. Zheng, K. Shaw-Saliba, R. Rothman, S. Eshleman, A. Pekosz, K. Hansen, H. Mostafa, M. Steinegger, H. B. Larman

This paper introduces cRASL-seq, a method for sensitive and high-throughput SARS-CoV-2 detection and genotyping without nucleic acid extraction or reverse transcription.

bioRxiv · Jun 3, 2020Pathology