Cancer BiologybioRxiv
RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4
H. N. W. Weinstein, K. Hu, L. Fish…·F. W. Huang
This study identifies RPL22 as a tumor suppressor in MSI-H cancers that regulates MDM4 splicing and reveals its role in oncogenic pathways.
DOI 10.1016/j.celrep.2024.114622