Spatially Resolved Phosphoproteomics Reveals Fibroblast Growth Factor Receptor Recycling-driven Regulation of Autophagy and Survival
J. Watson, H. R. Ferguson, R. M. Brady, J. Ferguson, P. Fullwood, H. Mo, K. H. Bexley, D. Knight, J.-M. Schwartz, M. P. Smith, C. Francavilla
The paper uses spatially resolved phosphoproteomics to show FGFR2b recycling activates mTOR and ULK1, suppressing autophagy and promoting cell survival in cancer cells.
bioRxiv · Dec 4, 2021Cell Biology