Author

H. S. Leong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Balakrishnan· 1 shared A. El-Sehemy· 1 shared A. J. Crawford· 1 shared B. A. Starich· 1 shared B. Kan· 1 shared B. Su· 1 shared C. M. Morshead· 1 shared C. Schuurmans· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Balakrishnan

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2 papers

Recent·Most cited

E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer

G. C. Russo, A. J. Crawford, D. J. Clark, J. Cui, R. Carney, M. N. Karl, B. Su, B. A. Starich, T.-S. Lih, P. Kamat, Q. Zhang, P.-h. Wu, M.-H. Lee, H. S. Leong, V. W. Rebecca, , D. Wirtz

This study shows E-cadherin interacts with EGFR to hyper-activate ERK, promoting proliferation in breast cancer models and identifying a potential therapeutic target.

bioRxiv · Nov 4, 2020Cancer Biology

SMPD3 suppresses IDH mutant tumor growth via dual autocrine-paracrine roles

A. Balakrishnan, F. Saleh, L. Adnani, V. Chinchalongporn, A. El-Sehemy, T. Olender, M. J. Chen, S. T. Ahmad, O. Prokopchuk, L. Vasan, Y. Touahri, R. Islam, S. Sujanthan, D. Zinyk, L. C. Comanita, , C. Schuurmans

This study shows SMPD3 suppresses IDH mutant glioma growth through autocrine and paracrine mechanisms, with higher SMPD3 linked to longer survival in patients.

bioRxiv · Jul 14, 2020 · PreprintCancer Biology