H. Strickfaden

Space-time dynamics of genome replication studied with super-resolved microscopy

The paper uses super-resolved microscopy to study genome replication dynamics in mouse myeloblast cells, revealing shifts in DNA compaction and labeling patterns during replication.

True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin

The paper presents true-to-scale DNA-density maps of human and mouse nuclei, revealing significant accessibility differences between active and inactive compartments.

Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells

This study shows that chromatin behaves like a solid on the mesoscale both in vitro and in living cells, with solid-like properties maintained despite limited fiber interactions.

KMT5C displays robust retention and liquid-like behavior in phase separated heterochromatin

This study identifies KMT5C as a protein with liquid-like behavior in phase-separated heterochromatin, showing limited nucleoplasmic exchange and spatial control.

A charge-dependent phase transition determines interphase chromatin organization

The paper investigates charge-dependent phase separation in chromatin using electron spectroscopic imaging and shows that chromatin organization changes with histone modifications and environmental factors.