Author

H. T. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Hanawa-Suetsugu· 2 shared S. Suetsugu· 2 shared T. Nishimura· 2 shared A. Mukherjee· 1 shared A. Nain· 1 shared B. Behkam· 1 shared C. Takahashi· 1 shared D. Matsubara· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

K. Hanawa-Suetsugu

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Author profile →

2 papers

Recent·Most cited

Actin filaments couple the protrusive tips to the nucleus through the I-BAR domain protein IRSp53 for migration of elongated cells on 1D fibers

A. Mukherjee, J. Ron, H. T. Hu, T. Nishimura, K. Hanawa-Suetsugu, B. Behkam, N. Gov, S. Suetsugu, A. Nain

This study shows that IRSp53 couples actin filaments to the nucleus via membrane curvature during 3D cell migration on 1D fibers, affecting protrusion and contractility.

bioRxiv · May 20, 2022 · PreprintCell Biology

Involvement of I-BAR protein IRSp53 in tumor cell growth via extracellular microvesicle secretion

H. T. Hu, N. Sasakura, D. Matsubara, N. Furusawa, M. Mukai, N. Kitamura, T. Obayashi, T. Nishimura, K. Oono-Yakura, Y. Funato, Y. Okamura, K. Tarao, Y. Nakano, Y. Murakami, K. Kinoshita, , S. Suetsugu

This study shows IRSp53 promotes tumor cell proliferation through microvesicle secretion, as evidenced by reduced secretion and phosphorylation in knockout cells and increased survival in IRSp53-deficient mice.

bioRxiv · Apr 20, 2020 · PreprintCell Biology