Author

C. Takahashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

S. Kohno· 2 shared A. H. Fahal· 1 shared A. Hasegawa· 1 shared A. Sawai· 1 shared A. Vajdi Hoojghan· 1 shared A. Verbon· 1 shared B. Nguyen· 1 shared C. Araki· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

S. Kohno

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Iron regulatory pathways differentially expressed during Madurella mycetomatis grain development in Galleria mellonella

I. Abugessaisa, M. Konings, R.-I. Manabe, T. Kawashima, A. Hasegawa, C. Takahashi, M. Tagami, Y. Okazaki, W. Lim, A. Verbon, A. H. Fahal, T. Kasukawa, W. Van de Sande

This study identifies iron regulatory pathways involved in Madurella mycetomatis grain formation in Galleria mellonella using time-course transcriptomic profiling.

bioRxiv · Dec 20, 2022 · PreprintMicrobiology

NFYA promotes the malignant behavior of triple-negative breast cancer through the regulation of lipid metabolism

N. Okada, C. Ueki, M. Shimazaki, G. Tsujimoto, S. Kohno, H. Muranaka, K. Yoshikawa, C. Takahashi

The paper shows NFYAv1 promotes TNBC malignancy by enhancing lipid metabolism, and targeting this axis could be a therapeutic strategy.

bioRxiv · May 26, 2022 · PreprintCancer Biology

The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

C. Noyes, S. Kitajima, F. Li, Y. Suita, S. Miriyala, S. Isaac, N. Ahsan, E. Knelson, A. Vajdi Hoojghan, T. Tani, T. Thai, D. Xu, J. Murai, N. Tapinos, C. Takahashi, , M. Yajima

This study shows DDX4, a germline factor, enhances chemoresistance and motility in SCLC cells by altering metabolism and EMT-like features.

bioRxiv · Apr 22, 2022Cancer Biology

Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells

N. Okahashi, T. Shima, Y. Kondo, C. Araki, S. Tsuji, A. Sawai, H. Uehara, S. Kohno, H. Shimizu, C. Takahashi, F. Matsuda

The paper uses metabolic flux analysis to show that cancer cells prefer aerobic glycolysis over oxidative phosphorylation due to reduced metabolic heat generation.

bioRxiv · Nov 16, 2021Cancer Biology

Involvement of I-BAR protein IRSp53 in tumor cell growth via extracellular microvesicle secretion

H. T. Hu, N. Sasakura, D. Matsubara, N. Furusawa, M. Mukai, N. Kitamura, T. Obayashi, T. Nishimura, K. Oono-Yakura, Y. Funato, Y. Okamura, K. Tarao, Y. Nakano, Y. Murakami, K. Kinoshita, , S. Suetsugu

This study shows IRSp53 promotes tumor cell proliferation through microvesicle secretion, as evidenced by reduced secretion and phosphorylation in knockout cells and increased survival in IRSp53-deficient mice.

bioRxiv · Apr 20, 2020 · PreprintCell Biology

Scaling up DNA data storage and randomaccess retrieval

L. Organick, S. D. Ang, Y.-J. Chen, R. Lopez, S. Yekhanin, K. Makarychev, M. Z. Racz, G. Kamath, P. Gopalan, B. Nguyen, C. Takahashi, S. Newman, H.-Y. Parker, C. Rashtchian, K. Stewart, , K. Strauss

This paper demonstrates large-scale DNA data storage with random access, storing 200MB of data in 13 million DNA oligonucleotides and achieving error-free retrieval.

bioRxiv · Mar 7, 2017Bioengineering