Author

S. Suetsugu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

K. Hanawa-Suetsugu· 3 shared T. Nishimura· 3 shared H. T. Hu· 2 shared K. Oono-Yakura· 2 shared N. Gov· 2 shared A. G. Amir· 1 shared A. Iglic· 1 shared A. Kitao· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

K. Hanawa-Suetsugu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Theoretical model of membrane protrusions driven by curved active proteins

Y. Ravid, S. Penic, Y. Mimori-Kiyosue, S. Suetsugu, A. Iglic, N. Gov

The paper extends a physical model of membrane protrusions driven by curved active proteins to explore the formation of different protrusive structures like lamellipodia and filopodia.

bioRxiv · Jan 31, 2023Biophysics

Actin filaments couple the protrusive tips to the nucleus through the I-BAR domain protein IRSp53 for migration of elongated cells on 1D fibers

A. Mukherjee, J. Ron, H. T. Hu, T. Nishimura, K. Hanawa-Suetsugu, B. Behkam, N. Gov, S. Suetsugu, A. Nain

This study shows that IRSp53 couples actin filaments to the nucleus via membrane curvature during 3D cell migration on 1D fibers, affecting protrusion and contractility.

bioRxiv · May 20, 2022 · PreprintCell Biology

Activation of Nedd4L Ubiquitin Ligase by FCHO2-generated Membrane Curvature

Y. Sakamoto, A. Uezu, K. Kikuchi, S. Suetsugu, H. Nakanishi

This study shows that FCHO2-generated membrane curvature activates Nedd4L by relieving its autoinhibition, facilitating ENaC ubiquitination and endocytosis.

bioRxiv · Feb 21, 2022 · PreprintCell Biology

Translation of cellular protein localization by generative adversarial network

K. Shigene, Y. Hiasa, Y. Otake, M. Soufi, S. Janewanthanakul, T. Nishimura, Y. Sato, S. Suetsugu

This study uses a generative adversarial network to translate actin filament images into protein localization images, showing high similarity for actin-related proteins but lower for microtubules.

bioRxiv · Apr 23, 2021Cell Biology

Involvement of I-BAR protein IRSp53 in tumor cell growth via extracellular microvesicle secretion

H. T. Hu, N. Sasakura, D. Matsubara, N. Furusawa, M. Mukai, N. Kitamura, T. Obayashi, T. Nishimura, K. Oono-Yakura, Y. Funato, Y. Okamura, K. Tarao, Y. Nakano, Y. Murakami, K. Kinoshita, , S. Suetsugu

This study shows IRSp53 promotes tumor cell proliferation through microvesicle secretion, as evidenced by reduced secretion and phosphorylation in knockout cells and increased survival in IRSp53-deficient mice.

bioRxiv · Apr 20, 2020 · PreprintCell Biology

Regulation of caveolae through cholesterol-depletion dependent tubulation by PACSIN2/Syndapin II

A. G. Amir, K. Takemura, K. Hanawa-Suetsugu, K. Oono-Yakura, K. Yasuhara, A. Kitao, S. Suetsugu

This study shows that PACSIN2-mediated membrane tubulation and caveolae internalization are regulated by cholesterol levels in the plasma membrane.

bioRxiv · Mar 25, 2020Cell Biology