H. Takeshima

Mitochondrial DNA analysis in ayu (Plecoglossus altivelis) raises an urgent conservation need for its southernmost population

This study analyzes mitochondrial DNA in ayu populations to test the central-marginal hypothesis, finding low genetic diversity and significant differentiation in southern marginal populations.

Non-physiologic interaction of MG53 with insulin receptor and lack of evidence for MG53's role in controlling insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues.

This study investigates whether MG53 interacts with the insulin receptor and affects Akt phosphorylation in muscle, heart, and liver tissues, finding low binding affinity and no effect on insulin signaling.

Probe capture enrichment sequencing of amoA genes discloses diverse ammonia-oxidizing archaeal and bacterial populations

This study develops a probe capture enrichment method for amoA genes, revealing more accurate and diverse ammonia-oxidizing archaeal and bacterial populations than traditional sequencing approaches.

C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth

This study identifies a signaling pathway involving CNP, NPR2, PKG, BK channels, and TRPM7 that facilitates Ca2+ entry in growth plate chondrocytes to stimulate bone growth.

DNA methylation site loss for plasticity-led novel trait genetic fixation

The paper investigates how epigenetic regulation loss leads to genetic fixation of novel traits in medaka fish through methylation profiling and CRISPR/Cas9 deletion.