Author

H. Akiyama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Gummuluru· 2 shared A. A. Quinones-Molina· 1 shared A. Ichimura· 1 shared A. L. Morey· 1 shared A. Nisa· 1 shared E. L. Suder· 1 shared E. Muhlberger· 1 shared E. Peters· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

S. Gummuluru

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Incorporation of 5 methylcytidine alleviates innate immune response to self-amplifying RNA vaccine

M. Komori, A. L. Morey, A. A. Quinones-Molina, J. Fofana, L. Romero, E. Peters, K. Matsuda, S. Gummuluru, J. F. Smith, W. Akahata, H. Akiyama

This study shows that incorporating 5-methylcytidine into saRNA vaccines reduces innate immune activation and adverse effects while maintaining strong immune responses.

bioRxiv · Nov 1, 2023 · PreprintImmunology

CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses

S. Jalloh, J. Olejnik, J. Berrigan, A. Nisa, E. L. Suder, H. Akiyama, M. Lei, S. Tyagi, Y. Bushkin, E. Muhlberger, S. Gummuluru

This study shows CD169 enables ACE2-independent SARS-CoV-2 entry in macrophages, leading to restricted viral replication and pro-inflammatory cytokine production.

bioRxiv · Mar 29, 2022Immunology

C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth

Y. Miyazaki, A. Ichimura, R. Kitayama, N. Okamoto, T. Yasue, F. Liu, Y. Ueda, I. Yamauchi, T. Hakata, K. Nakao, S. Kakizawa, M. Nishi, Y. Mori, H. Akiyama, K. Nakao, H. Takeshima

This study identifies a signaling pathway involving CNP, NPR2, PKG, BK channels, and TRPM7 that facilitates Ca2+ entry in growth plate chondrocytes to stimulate bone growth.

bioRxiv · Sep 17, 2021Cell Biology