Author

H. Tsuge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Herrmann· 1 shared A. Kawamoto· 1 shared A. Meents· 1 shared A. Sekirnik· 1 shared A. Usenik· 1 shared D. Turk· 1 shared G. Ebert· 1 shared H. N. Chapman· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. Herrmann

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2 papers

Recent·Most cited

Structural elucidation and antiviral activity of cathepsin L inhibitors with carbonyl and epoxide warheads

S. Falke, J. Lieske, A. Herrmann, J. Loboda, S. Gunther, P. Y. A. Reinke, W. Ewert, K. Karnicar, A. Usenik, N. Lindic, A. Sekirnik, H. Tsuge, V. Turk, H. N. Chapman, W. Hinrichs, , A. Meents

The paper presents crystal structures of cathepsin L inhibitors and evaluates their antiviral activity against SARS-CoV-2.

bioRxiv · Aug 11, 2023 · PreprintBiochemistry

Translocational unfolding in clostridial binary iota toxin complex

T. Yamada, T. Yoshida, A. Kawamoto, K. Mitsuka, K. Iwasaki, H. Tsuge

This study reports the structure of the clostridial binary toxin translocation channel and its complex with ADP-ribosyltransferase, revealing a novel mechanism of N-terminal unfolding for protein translocation.

bioRxiv · Aug 1, 2019 · PreprintBiophysics