Author

H. U. Osmanbeyoglu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Bostwick· 1 shared A. J. Cipriano· 1 shared C. J. Bakkenist· 1 shared D. Palmer· 1 shared F. P. Vendetti· 1 shared G. M. Delgoffe· 1 shared J. H. Beumer· 1 shared J. J. Deppas· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Bostwick

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3 papers

Recent·Most cited

Single-cell analysis reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of ovarian cancer

L. Zhang, S. Cascio, J. W. ellors, R. J. Buckanovich, H. U. Osmanbeyoglu

The paper uses single-cell transcriptomics to analyze ovarian cancer microenvironment dynamics, identifying CXCL12-CXCR4 interactions that drive immunosuppression in high-stromal tumors.

bioRxiv · Jun 7, 2023Cancer Biology

Chromatin accessibility landscape and active transcription factors in primary human invasive lobular and ductal breast carcinomas

S. Lee, H. U. Osmanbeyoglu

The paper compares chromatin accessibility and active transcription factors between invasive lobular and ductal breast carcinomas using ATAC-seq data from TCGA.

bioRxiv · Apr 8, 2022Cancer Biology

Thymidine rescues ATR kinase inhibition induced deoxyuridine contamination in genomic DNA, cell death, and Type 1 interferon expression

N. Sugitani, F. P. Vendetti, A. J. Cipriano, P. Pandya, J. J. Deppas, T. N. Moiseeva, S. Schamus-Haynes, Y. Wang, D. Palmer, H. U. Osmanbeyoglu, A. Bostwick, N. W. Snyder, Y.-N. Gong, K. M. Aird, G. M. Delgoffe, , C. J. Bakkenist

This study shows that thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination, cell death, and Type 1 interferon expression in CD8+ T cells.

bioRxiv · Feb 24, 2022 · PreprintCancer Biology