Author

D. Palmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Bostwick· 1 shared A. Charap· 1 shared A. J. Cipriano· 1 shared A. M. Farkas· 1 shared A. M. Schlitter· 1 shared A. Mielgo· 1 shared A. O. Kamphorst· 1 shared A. Taylor· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCancer Biology

A. Bostwick

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

B. Salome, J. P. Sfakianos, J. Daza, A. Charap, C. Hammer, R. Banchereau, A. M. Farkas, D. Geanon, G. Kelly, R. M. de Real, B. Lee, K. G. Beaumont, S. Shroff, Y. S. A. Wang, Y.-C. Wang, , Mariath

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

bioRxiv · Mar 4, 2022 · PreprintImmunology

Thymidine rescues ATR kinase inhibition induced deoxyuridine contamination in genomic DNA, cell death, and Type 1 interferon expression

N. Sugitani, F. P. Vendetti, A. J. Cipriano, P. Pandya, J. J. Deppas, T. N. Moiseeva, S. Schamus-Haynes, Y. Wang, D. Palmer, H. U. Osmanbeyoglu, A. Bostwick, N. W. Snyder, Y.-N. Gong, K. M. Aird, G. M. Delgoffe, , C. J. Bakkenist

This study shows that thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination, cell death, and Type 1 interferon expression in CD8+ T cells.

bioRxiv · Feb 24, 2022 · PreprintCancer Biology

GATA4 and GATA6 loss-of-expression is associated with extinction of the classical programme and poor outcome in pancreatic ductal adenocarcinoma

M. P. de Andres, R. Jackson, C. Pilarsky, A. M. Schlitter, E. Costello, W. Greenhalf, P. Ganeh, T. Knoesel, D. Palmer, P. Ruemmele, W. Weichert, M. Buechler, T. Hackert, J. P. Neoptolemos, N. Malats, , F. X. Real

This study shows that low GATA4 and GATA6 expression in pancreatic ductal adenocarcinoma (PDAC) is linked to worse patient outcomes and loss of the classical tumor phenotype.

bioRxiv · Aug 9, 2021Cancer Biology

Recurrent human papillomavirus-related head and neck cancer undergoes metabolic re-programming and is driven by oxidative phosphorylation

A. VYAS, R. A. Harbison, D. Faden, M. Kubik, D. Palmer, Q. Zhang, H. Osmanbeyoglu, E. Mendez, U. Duvvuri

This study identifies oxidative phosphorylation as a driver of treatment failure in recurrent HPV-related head and neck cancer, highlighting Nrf2 as a therapeutic target.

bioRxiv · Aug 21, 2020Cancer Biology

A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular Senescence

K. Chatsirisupachai, D. Palmer, S. Ferreira, J. P. de Magalhaes

This study compares age-related and cancer gene expression changes across nine human tissues, finding opposing trends and highlighting the role of cellular senescence in ageing and its potential to hinder cancer.

bioRxiv · Mar 31, 2019Cancer Biology

Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer

V. Quaranta, C. Rainer, S. R. Nielsen, M. Raymant, M. S. Ahmed, D. Engle, A. Taylor, T. Murray, F. Campbell, D. Palmer, D. Tuveson, A. Mielgo, M. Schmid

This study shows that macrophage-derived granulin promotes resistance to immune checkpoint inhibitors in metastatic pancreatic cancer by excluding CD8+ T cells, and blocking granulin improves anti-tumor immunity.

bioRxiv · Dec 15, 2017Cancer Biology