H. Xing

Translation dynamics in human cells visualized at high-resolution reveal cancer drug action

The paper visualizes ribosome dynamics in human cells at near-atomic resolution, revealing how a cancer drug alters translation.

Cooperatively Designed Aptamer-PROTACs for Spatioselective Degradation of Nucleocytoplasmic Shuttling Protein for Enhanced Combinational Therapy

This paper introduces PS-ApTCs, a novel PROTAC design using aptamers for spatioselective degradation of nucleocytoplasmic shuttling proteins, showing enhanced efficacy and synergistic effects in cancer therapy.

A De Novo regulation design shows an effectiveness in altering plant secondary metabolism

This study designs a de novo regulation system using TFs and CREs to alter plant secondary metabolism, showing reduced tobacco alkaloids and nitrosamines in engineered plants.

An In situ Collagen-HA Hydrogel System Promotes Survival and Preserves the Proangiogenic Secretion of hiPSC-derived Vascular Smooth Muscle Cells

This study evaluates a collagen-HA hydrogel system for supporting hiPSC-VSMC survival and proangiogenic secretion, showing improved viability and growth factor release.

The microRNA476a/RFL module regulates adventitious root formation through a mitochondria-dependent pathway in Populus

This study identifies miR476a/RFL as a regulator of adventitious root formation in poplar through mitochondrial homeostasis and auxin pathway modulation.

Rapid CD4 cell loss is caused by specific CRF01_AE cluster with V3 signatures favoring CXCR4 usage

The paper identifies a specific CRF01_AE HIV-1 phylogenetic cluster associated with rapid CD4 cell loss and higher prevalence of CXCR4-using viruses.