Author

K. Duan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Biochemistry· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 8 Research Focus:cell type annotation· 6 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

B. C. Dash· 3 shared H. Hsia· 2 shared J. Lu· 2 shared J. Yu· 2 shared X. Yang· 2 shared Z. WangiD· 2 shared A. K. Andiappan· 1 shared A. Prassinos· 1 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersBioengineering

B. C. Dash

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Tradeoffs in ATP metabolisms via hypoxic gradient migration assays

M. Orabi, K. Duan, M. Zhou, J. F. Lo

The paper develops a microfluidic assay to study ATP metabolism tradeoffs in HaCaT cells under hypoxia and hyperglycemia, revealing a metabolic switch between stationary and motile modes.

bioRxiv · Apr 6, 2024 · PreprintBioengineering

Reduction in mRNA expression of the neutrophil chemoattract factor CXCL1 in Pseudomonas aeruginosa treated Barth Syndrome B lymphoblasts

H. M. Zegallai, K. Duan, G. M. Hatch

The paper examines CXCL1 mRNA expression in BTHS B lymphoblasts before and after Pseudomonas aeruginosa treatment, finding significant reductions in both conditions.

bioRxiv · Apr 18, 2023Biochemistry

Transcriptional heterogeneity in diabetic foot wounds

T. Sandoval-Schaefer, Q. Phan, B. Dash, A. Prassinos, K. Duan, M. I. Gazes, S. D. Vyce, H. C. Hsai, R. Driskell, V. Horsley

This study uses single-cell RNA sequencing to identify transcriptional changes in diabetic foot ulcers compared to non-diabetic wounds, revealing defects in keratinocyte differentiation, fibroblast function, and macrophage metabolism.

bioRxiv · Feb 16, 2023 · PreprintCell Biology

Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

X. Li, Y. Pan, Q. Yin, Z. Wang, S. Shan, L. Zhang, J. Yu, Y. Qu, L. Sun, F. Gui, J. Lu, Z. Jing, W. Wu, T. Huang, X. Shi, , X. Wang

This study identifies two broadly neutralizing antibodies against SARS-CoV-2 variants and shows their synergistic neutralization effect, supported by cryo-EM structures.

bioRxiv · May 27, 2022Biochemistry

iPSC-derived Vascular Smooth Muscle Cells in a Fibronectin Functionalized Collagen Scaffold Augment Endothelial Cell Morphogenesis

K. Duan, B. C. Dash, D. Sasson, H. Hsia

This study shows that fibronectin and hiPSC-derived vascular smooth muscle cells enhance endothelial network formation in 3D scaffolds.

bioRxiv · Jul 22, 2021Bioengineering

Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

C. Li, D. Yu, X. Wu, H. Liang, Z. Zhou, Y. Xie, T. Li, J. Wu, F. Lu, L. Feng, M. Mao, L. Lin, H. Guo, S. Yue, F. Wang, , X. Yang

The study tracks IgG antibody levels against SARS-CoV-2 RBD in convalescent plasma donors over 12 months, showing sustained positivity and gender/age-related differences.

bioRxiv · Apr 5, 2021Immunology

Data-driven analysis of COVID-19 reveals specific severity patterns distinct from the temporal immune response

J. Lim, G. Carissimo, Y.-H. Chan, S.-W. Fong, W. W. Lee, S.-Y. Tan, D. C. Lye, B. E. Young, L. Renia, L. Fong-Poh NG, O. Rotzschke, K. J. Puan, L. W. Wang, K. W. W. Teng, C. Y. Loh, , B. Lee

The paper identifies immune signatures associated with COVID-19 severity and temporality, revealing distinct patterns and providing tools for data analysis.

bioRxiv · Feb 10, 2021 · PreprintImmunology

Integrin β3 Targeting Biomaterial Preferentially Promotes Secretion of bFGF and Proliferation of iPSC-Derived Vascular Smooth Muscle Cells

B. C. Dash, K. Duan, T. Kyriakides, H. Hsia

This study shows that targeting integrin β3 in hiPSC-VSMCs increases bFGF secretion and cell proliferation via fibronectin interactions and a positive feedback loop with MMP-2.

bioRxiv · Jan 6, 2021Bioengineering

An In situ Collagen-HA Hydrogel System Promotes Survival and Preserves the Proangiogenic Secretion of hiPSC-derived Vascular Smooth Muscle Cells

B. C. Dash, K. Duan, H. Xing, T. R. Kyriakides, H. C. Hsia

This study evaluates a collagen-HA hydrogel system for supporting hiPSC-VSMC survival and proangiogenic secretion, showing improved viability and growth factor release.

bioRxiv · Jun 6, 2020Bioengineering

SPARSE INFOMAX BASED ON HOYER PROJECTION AND ITS APPLICATION TO SIMULATED STRUCTURAL MRI AND SNP DATA

K. Duan, R. F. Silva, J. Chen, D. Lin, V. D. Calhoun, J. Liu

This paper introduces a sparse infomax algorithm using Hoyer projection for improved pattern recovery in simulated structural MRI and SNP data, showing better sparseness and performance under low signal-to-noise ratio conditions.

bioRxiv · Mar 7, 2019 · PreprintBioengineering